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The Institute for Ageing and Health
University of Newcastle
International Centre for Life, Newcastle-Upon-Tyne, UK
14-16 July 2003
The UK-Japan Conference ‘Horizons in Ageing and Health’ which will take place in Newcastle upon Tyne, July 14-16, 2003. The unique focus of the meeting will be on recent understanding of the primary mechanisms of ageing and how this can lead to the identification of new targets for therapies.
This exciting and timely conference will bring together researchers from universities, government research institutes, and the pharmaceutical and biotechnology industries. Presentations and discussions will consider how the upstream mechanisms of ageing, such as oxidative stress, genetic and protein damage determine susceptibility to the age-related pathologies of organs including brain, heart, skin, muscle and gut, and the implications of these mechanisms for therapeutic interventions.
The conference will be held at the International Centre for Life, North East England's outstanding science venue, and is being hosted by the University of Newcastle’s Institute for Ageing and Health, one of Europe’s leading centres for interdisciplinary research into ageing and age-related disorders. It will coincide with, and report to, the 18th UK-Japan High Technology Industries Forum which attracts the most senior leaders, R&D directors and researchers from high-tech industry and university centres of excellence in Japan and the UK, and is being held in Newcastle later the same week. One of the major topics being considered by the Forum this year is the challenges and opportunities for industry posed by an ageing society.
We hope you will take the opportunity to attend this conference and visit the vibrant city of Newcastle upon Tyne. Renowned for its warm and friendly welcome, the city offers history, a rich variety of culture, a wide variety of restaurants and night clubs, as well as some excellent shopping, sport and leisure facilities. The surrounding area has some of Britain’s most beautiful coastline and countryside, and hosts two world heritage sites, Hadrian’s Wall and, Durham Cathedral and Castle.
PROGRAMME: Sessions and Topics
Conference Theme: How new scientific understanding of the ageing process can lead to the identification of new targets for intervention and therapy to combat age-related frailty, disability and disease. Sessions will consist of scientific papers commented on in some cases by a Lead Discussant followed by general discussion. Posters will be on continuous display.
Please note, all sessions will be presented in English. Some speakers to be confirmed.
SUNDAY 13 JULY 2003
2pm onwards Arrival and Registration
7.30pm Welcome Reception at Vermont Hotel
MONDAY 14 JULY 2003
Time Session Speaker
9.00-11.00am Session 1 THE CHALLENGE OF AGEING
Welcome and Introduction
Ageing: Challenges and Opportunities for Academia and Industry
New Scientific Understanding of the Ageing Process
Interventions in Ageing and Age-Related Disorders: Pharmacological and Nutritional Approaches
Immunological Restoration; A Challenge to Cope with Age-associated Diseases
General Discussion
Professor Christopher Edwards, Vice Chancellor, University of Newcastle upon Tyne
Dr Takeshi Tabira, Director, National Institute for Longevity Sciences (NILS), Obu
Professor Tom Kirkwood, Newcastle
Dr Kenichi Kitani, Obu
Professor Katsuiku Hirokawa, Tokyo
11.00-11.30am COFFEE AND POSTERS
11.30-1.15pm Session 2 UPSTREAM MECHANISMS OF AGEING I
DNA Damage and Repair
Stress Responses and Ageing
Telomeres and Telomerase
Mitogen-activated protein kinase p38 defines the common senescence-signaling pathway
General Discussion
Dr Yvonne Barnett, Coleraine
Dr Kenichi Isobe, NILS
Professor Thomas von Zglinicki, Newcastle
Professor Fuyuki Ishikawa, Kyoto
1.15-2.15pm LUNCH AND POSTERS
2.15-4.00pm Session 3 UPSTREAM MECHANISMS OF AGEING II
Molecular background of age-associated organ disorders
Protein Oxidation and Degradation
Free Radicals and Ageing
Mitochondrial Genome Polymorphisms
General Discussion
Dr Naoki Maruyama, Tokyo
Professor Sataro Goto, Funabashi
Dr Mike Murphy, Cambridge
Dr Masashi Tanaka, Gifu
4.00-4.30pm TEA AND POSTERS
4.30-5.45pm Session 4 UPSTREAM MECHANISMS OF BRAIN AGEING
Nicotine Receptors and Neuroprotection
Aß Metabolism and Alzheimer's disease
From Neurodegeneration to Neuroprotection: the Role of Ubiquitin
General Discussion
Professor Elaine Perry, Newcastle
Dr Takaomi Saido, Wako
Professor John Mayer, Nottingham
7.00-9.00pm INFORMAL BUFFET DINNER AT ‘LIFE INTERACTIVE’, INTERNATIONAL CENTRE FOR LIFE
TUESDAY 15 JULY 2003
Time Session Speaker
9.00-10.45am Session 5 UPSTREAM MECHANISMS OF BRAIN AGEING II
Significance of ageing and cholesterol in Alzheimer's disease
Molecular Substrates of Vascular Dementia
Neuronal Shcs and neuronal GAPs: Regulators of neural development, regeneration, plasticity, and brain ageing
Tau Deposition in Neurodegenerative Disease
General Discussion
Dr Katsuhiko Yanagisawa, Obu
Professor Raj Kalaria, Newcastle
Dr Nozomu Mori, Obu
Dr Diane Hanger, London
10.45-11.15am COFFEE AND POSTERS
11.15-1.00pm Session 6 UPSTREAM MECHANISMS OF MUSCULO-SKELETAL AGEING
Molecular Stress and Muscle Ageing
Bone Resorption as a Target of Osteoporosis Therapy
Regulation of the Extracellular Matrix
Klotho: A Fundamental regulator of calcium homeostasis
General Discussion
Dr Anne McArdle, Liverpool
Dr Kyoji Ikeda, Obu
Dr Hideaki Nagase, London
Professor Yo-ichi Nabeshima, Kyoto
1.00-2.00pm LUNCH AND POSTERS
2.00-4.00pm Session 7 OTHER ORGANS
Intrinsic Ageing of Skin
Error Prone DNA Polymerases: Implications for Carcinogenesis and Ageing
Ageing of the Gut
Age-Related Macular Degeneration
Title to be announced
General Discussion
Dr Martin Green, Colworth
Professor Fumio Hanaoka, Osaka
Dr Tim Cowen, London
Dr Norman McKie, Newcastle
Professor Roy Quinlan, Durham
4.00-4.30pm TEA AND POSTERS
4.30-5.45pm Session 8 STEM CELL AGEING
Ageing of Epithelial Stem Cells
Mitochondrial DNA Mutation and Ageing Stem Cells
Ageing of Haemopoietic Stem Cells
General Discussion
Dr Cath Booth, Manchester
Dr Rob Taylor, Newcastle
Dr Linda Lako, Newcastle
7.30 for 8.00pm CONFERENCE DINNER, OLD ASSEMBLY ROOMS
WEDNESDAY 16 JULY 2003
Time Session Speaker
9.00-10.15pm Session 9 GENOMIC APPROACHES TO AGEING
Gene Regulation and the Development of Age Dimension Technology
Cardiovascular Ageing
Strategies to Identify Genes for Complex Diseases
General Discussion
Dr Kotuku Kurachi, Tsukuba
Dr Bernard Keavney
Professor Tetsuro Miki, Ehime
10.15-11.00am Session 10 POPULATION-BASED STUDIES OF AGEING
The MRC Cognitive Function in Ageing Study (CFAS)
Tokyo Centenarian Study: Multi-disciplinary Approaches to the Oldest Old
General Discussion
Professor Paul Ince, Sheffield
Dr Nobuyoshi Hirose, Tokyo
11.00-11.30am COFFEE
11.30am-1.00pm Session 11 FROM BASIC SCIENCE TO INDUSTRY: BUILDING BRIDGES Round Table Format – details and lead discussants to be announced
1.00-2.00pm LUNCH AND POSTERS
2.00-3.00pm Session 12 TAKE HOME MESSAGES FOR ACADEMIA AND INDUSTRY
Take Home Messages for Academia
Take Home Messages for Industry
Dr Takeshi Tabira, Obu
Dr Fred Wright, Newcastle
3.00-3.30pm CLOSING THANKS AND TEA
BOOKING:
Delegate Booking Instructions
Please read these instructions carefully before completing the attached booking form.
Please print clearly your contact details and choice of payment.
Payment must be received in full before attending the conference.
Confirmation of your booking will be sent to you with full travel details.
Conference Fees
Industry Conference Package – Three day Conference Package & Social Events ~ £550
This is for delegates in industry attending the conference and includes all sessions, lunch, refreshments, welcome reception and the Conference Dinner on Tuesday evening.
Academic Conference Package - Three day Conference Package & Social Events ~ £295
This is for academic delegates attending the conference and includes all sessions, lunch, refreshments, and the Conference Dinner on Tuesday evening.
Social Events
A welcome reception will be held on Sunday 13 July at the Vermont Hotel, largely for the Japanese delegates prior to the conference. A second evening reception will be hosted at the International Centre for Life on Monday 14 July. The Conference Dinner is to be held at The Assembly Rooms on Tuesday 15 July.
A map of Newcastle upon Tyne showing the hotels and the International Centre for Life appears in the travel and accommodation section of this web site.
Travel bursaries
The Great Britain Sasakawa Foundation has provided support towards the travel costs of Japanese academics. Funds will be available in the region of £400. Early application is advised, as a limited number of places are available. To apply for this assistance with travel costs please complete the form below: